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Thyroid Hormone Receptors

Softcover - 9781489938794
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Beschreibung

A panel of outstanding investigators surveys and explains the major cutting-edge methods used in thryroid receptor (TR) research and explains their practical experimental details. Described in step-by-step detail to ensure robust experimental results, the techniques presented cover a wide variety of key areas, including TR in development and knockout (mouse and Xenopus), transcriptional regulation by TRs in both cell-free systems and in living cells, and TR mutant analysis of patients. Additional methods provide powerful tools for the isolation of TR-regulated protein complexes, for studying the oncogene v-Erba in blood cell differentiation, and for target gene analysis in the brain. Microarray chip methods are also presented for analyzing the organs of transgenic mice to identify target genes in the liver.

Methods and Protocols

Methods and Protocols

Details

Verlag Humana Press
Ersterscheinung August 2013
Maße 22.9 cm x 15.2 cm
Gewicht 349 Gramm
Format Softcover
ISBN-13 9781489938794
Auflage Softcover reprint of the original 1st edition 2002
Seiten 223

Schlagwörter