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The GABA Receptors

Hardcover - 9781588298133
213,99 €
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Softcover - 9781627038959
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Weitere Formate

Softcover - 9781627038959
213,99 €

Beschreibung

This volume is the third edition of a monograph series that was first published in 1983. The demand for this work is a testament to the impact of studies on -aminobutyric acid (GABA) receptors on the basic understanding of synaptic transmission and on defining the clinical importance of the neurotransmitter system. Chronicled in The GABA Receptors, Third Edition, are the advances made in understanding the molecular and pharmacological properties of GABA A and GABA receptors since the topic was last reviewed in 1996. Particular B emphasis is placed on describing the assembly, structure, and function of GABA B sites, the first heterodimeric G protein-coupled receptors identified in vivo. In addition, there are reports dealing with the subunit composition, trafficking, and pharmacological selectivity of GABA receptors. Aside from providing A insights into the fundamental properties of ligand-gated ion channels and second messenger systems, the findings detailed in this work point the way for developing novel therapeutics capable of more selectively manipulating these transmitter sites.

Details

Verlag Humana Press
Ersterscheinung 19. Juli 2007
Maße 22.9 cm x 15.2 cm
Gewicht 670 Gramm
Format Hardcover
ISBN-13 9781588298133
Auflage 3rd ed. 2007
Seiten 325

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