The Coenzyme Q10 and Antioxidant Vitamins in Renal Failure

Renal failure (RF) is a disease in which the kidneys are no longer enable to process the body wastes. There are two types of RF acute renal failure and chronic renal failure. Dialysis is a process by which the problems from impairment of renal function is filled and divided into two types peritoneal and hemodialysis. The book is designed to investigate the levels of MDA and CoQ10 in serum of RF patients predialysis and postdialysis, by taking the serum of 40 RF patients and compare the results with healthy normal people. The level of MDA was significantly (P<0.01) higher in RF patients compared to control, and increased significantly (P<0.01) after dialysis. CoQ10 level was reduced significantly in RF patients compared to control but no significant differences has observed between the patient's CoQ10 levels before and after dialysis. The level of CoQ10 has shown significant negative association with age before dialysis but with BMI after dialysis. The hemodialysis process is linked with the increase of oxidative stress in RF patients and thus would drive further health complications.