The Cholesterol Story

The Cholesterol Story is a success story because it has helped diminish suffering and death for millions of people worldwide. Vast experimental studies have established the importance of cholesterol in causing the arterial disease atherosclerosis. Atherosclerosis is a disease of the vessel wall that can lead to clinical symptoms like acute myocardial infarction or stroke. The ability to reduce levels of cholesterol in the blood has revolutionized the prevention andtreatment of cardiovascular disease. The importance of cholesterol in the development of arterial atherosclerosis has long been called the cholesterol hypothesis. With the recent expansion of knowledge about the role of cholesterol in this process, the alternative term cholesterol principle has been proposed, or, more specifically, the LDL principleor apolipoprotein B principle.This book should appeal to investigators and clinicians in the field of lipidology and lipid metabolism including physicians and cardiologists, researchers, fellows, medical students, dieticians and exercise physiologists, among others who are interested in preventive cardiology.