Autorenfreundlich Bücher kaufen?!
Beschreibung
The purpose of this research was to mask the intensely bitter taste of Lumefantrine and to formulate oral-disintegrating tablet (ODT) of Artemether & Lumefantrine. Taste masking was done by complexing Lumefantrine with amino alkyl methacrylate copolymer (Eudragit E - 100) using solvent deposition method and acetone as a solvent for pH-sensitive polymer and was tested for drug content and in vitro taste in simulated salivary fluid (SSF) of pH 6.8. The complex with drug polymer ratio of 1: 0.1 that did not release drug in SSF was considered taste-masked and selected for formulation of ODTs.
Oral Disintegrating Tablet Dosage Form of Artemether and Lumefantrine
Details
| Verlag | LAP LAMBERT Academic Publishing |
| Ersterscheinung | 12. April 2012 |
| Maße | 22 cm x 15 cm x 0.6 cm |
| Gewicht | 143 Gramm |
| Format | Softcover |
| ISBN-13 | 9783848482788 |
| Seiten | 84 |
Schlagwörter
Bekannt durch
