Synthesis of Some Biological Active Compounds

The versatile application of nitrogen and / or oxygen heterocyclic compounds have made this area of extensive research of synthetic chemists. Nitrogen heterocyclic compounds like triazines, Benzimidazoles, pyrazoles, isoxazoles and pyridines have received considerable attention in recent years due to their wide physiological activities. These derivatives are very useful in various fields e.g. drugs dyes, polymers, textiles, agricultures etc. Triazine derivatives have been used as antimicrobial herbicides, urinary antiseptics and anti-inflammatory agents. Benzimidazole derivatives have been reported to posses wide range of biological activities such as antibacterial, antifungal, antiviral and antihelmintic. In the light of the survey it is observed that there is not a single attempt to synthesize s-triazine derivatives incorporating with dihydrophyridine and coumarinyl moieties. Benzimidazoles also received less attention incorporating with ¿ N- substituted dihydropyridine, pyrazoline and Isoxazoline moieties, therefore the attempt was made to synthesize these compounds.The structure activity relationship were discussed in this book.