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Beschreibung
¿-Lactams, being a structural motif in most widely used antibiotics, have occupied a pivotal position in medicinal chemistry for almost a century now. With the microorganisms retaliating the traditional antibiotics via ¿-lactamase enzymes, the need for novel antibiotics prevails making the synthesis of newer ¿-lactams ever more important. Besides their use as antibiotics, ¿-lactams are increasingly being used as synthons for biologically important molecules. ¿-Lactams have been found to act as cholesterol acyltransferase inhibitors, thrombin inhibitors, human cytomegalovirus protease inhibitors, matrix metalloprotease inhibitors, cysteine protease, and apoptosis inductors.
Details
| Verlag | LAP LAMBERT Academic Publishing |
| Ersterscheinung | 06. November 2018 |
| Maße | 22 cm x 15 cm x 3.7 cm |
| Gewicht | 929 Gramm |
| Format | Softcover |
| ISBN-13 | 9786139936540 |
| Seiten | 612 |
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