Synthesis of N-Methyl triazolone derivatives as Antitubercular agent

Lots of modifications have been made during last decades on Triazolone nucleus and their derivatives have been studied extensively for their biological activities. A survey of literature revealed that these Triazolone derivatives possess different types of potential biological activities that include Antioxidant, antifungal, antihaemostatic, antibacterial, substituted aromatic aldehyde moiety with Triazolone nucleus for the first time has been associated to be designed for biological activity. As Triazolone nucleus moiety possess potent anti-tubercular activity. From all the above forgoing facts it was thought and considered to be very interesting to synthesis new series of Triazolone derivatives fused with aromatic Aldehyde for anti-tubercular activity.