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Beschreibung
Acridone derivatives containing 1, 3, 4-oxadiazole and 1, 3, 4-thiadiazole rings are synthesized.Diphenylamine-2,4`-dicarboxylic acid [1] is obtained in a high yield by refluxing a mixture of 4-aminobenzoic acid and 2-chloro benzoic acid in the presence of catalytic amount of copper oxide. 9(10H)-Acridone-2-carboxylic acid [2] is synthesized in ring closure reaction by heating compound [1] in sulfuric acid followed by basic hydrolysis.Reaction of compound [2] with thiosemicarbazide in the presence of phosphorus oxychloride gave 2-[5-amino-1, 3, 4-thiadiazole-2-yl]-9(10H)-acridone
SYNTHESIS OF SOME NEW HETEROCYCLIC COMPOUNDS CONTAINING 9(10H)-ACRIDONE, AND STUDYING THEIR BIOLOGICAL ACTIVITY
Details
| Verlag | LAP LAMBERT Academic Publishing |
| Ersterscheinung | 06. Juni 2011 |
| Maße | 22 cm x 15 cm x 0.6 cm |
| Gewicht | 149 Gramm |
| Format | Softcover |
| ISBN-13 | 9783844327861 |
| Seiten | 88 |
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