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Beschreibung
A novel [1,2,4]triazolo[4,3-c]pyrimidine-8-carboxamide libraries were synthesized via oxidative cyclization of hydrazono-1,6-dihydropyrimidine-5-carboxamide intermediates by the application of Iodobenzenediacetate as a sole cyclizating agent. Here, we report one pot sequential strategy to generate corresponding triazolopyrimidines by condensation of preprepared ¿-acylketene dithioacetals and arylamidines. Moreover, this process describes the application of presynthesized arylamidines which omits the transition metal catalyzed Suzuki-Miyaura cross coupling reaction hence signify the atom- and step-economic methodology.
Details
| Verlag | LAP LAMBERT Academic Publishing |
| Ersterscheinung | 01. August 2019 |
| Maße | 22 cm x 15 cm x 0.6 cm |
| Gewicht | 149 Gramm |
| Format | Softcover |
| ISBN-13 | 9783659639852 |
| Seiten | 88 |
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