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Beschreibung
The aim of the present study is to valorize the use in traditional medicine of Strychnos spinosa (Loganiaceae) as an antihypertensive plant. On isolated rat aorta pre-contacted with phenilephrine the crude extract of the plant causes endothelium-dependent vasorelaxation with a relaxation EC50 value equal to 0.900 ± 0.054 mg/ml. L-NAME inhibits the vasorelaxation effect induced by the extract of Strychnos spinosa with an increase in EC50 value of 2.254± 0.140mg/ml, this shows that the vasorelaxation effect involves a mechanism that involves NO. The inhibition of the effect by propranolol, with an EC50 of 2.762±0.138mg/ml demonstrates that the vasorelaxant effect involves the participation of ¿2 adrenergic receptors.
Details
| Verlag | Our Knowledge Publishing |
| Ersterscheinung | 28. Oktober 2021 |
| Maße | 22 cm x 15 cm x 0.4 cm |
| Gewicht | 96 Gramm |
| Format | Softcover |
| ISBN-13 | 9786204221991 |
| Seiten | 52 |
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