Spherical Agglomeration ; A Novel Technique of Particle Designing

Spherical agglomeration is a novel particle design method developed by kawashima et.al. It is also come under particle engineering technique in which crystallization and agglomeration carried out simultaneously.Many of the drugs administered by oral route because oral route administration is most convenient route for solid dosage forms. The basic requirement for commercial production of tablet is a particulate solid with good flowability, mechanical strength and compressibility. Hence is necessary to evaluate and manipulate the above said properties. To impart these properties the drugs are subjected to particle design techniques, spherical crystallization is one the techniques of particle design