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Role of serotonergic receptors in haloperidol induced EPS

Role of serotonergic receptors in haloperidol induced EPS

von Erum Shireen
Softcover - 9783659789465
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Beschreibung

Schizophrenia is a chronic, severe mental illness. The disease characterized by disturbed form and content of thoughts affects approximately 1% of the population. A goal of the current investigation was to alleviate the adverse effects of neuroleptics on motor behavior. The results of study indicates that serotonergic system, and particularly 5-HT-1A and 5-HT-2A/2C receptors, may be involved in the treatment of EPS induced by typical neuroleptics. It is suggested that serotonergic compounds with antidepressant activity may be of use for extending therapeutics in schizophrenia. The findings may help to develop antipsychotic agents with an improved therapeutic and smaller side effect profile.

Modulation of Haloperidol induced extrapyramidal motor side effects by different serotonergic drugs

Details

Verlag LAP LAMBERT Academic Publishing
Ersterscheinung 13. September 2017
Maße 22 cm x 15 cm x 2.1 cm
Gewicht 506 Gramm
Format Softcover
ISBN-13 9783659789465
Seiten 328