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Beschreibung
This volume evaluates the clinical patterns of resistance to sorafenib, the impact of trial design in the second-line setting and the current gold standard to define radiological resistance; describes the molecular mechanisms responsible for treatment resistance in HCC patients, including components of the immune system and tumor microenvironment; determines the role of the cancer stem cell phenotype in resistance; reviews the experimental models to study resistance; and addresses new approaches to overcome resistance to sorafenib, using successful examples from other malignancies.
Details
| Verlag | Springer International Publishing |
| Ersterscheinung | 27. Juli 2017 |
| Maße | 23.5 cm x 15.5 cm |
| Gewicht | 418 Gramm |
| Format | Hardcover |
| ISBN-13 | 9783319561967 |
| Seiten | 147 |
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