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Pyrazolo[1,5-a][1,3,5]triazine synthesis & diverse biological activity

Pyrazolo[1,5-a][1,3,5]triazine synthesis & diverse biological activity

von Khaled Abouzid und Mazin Najm
Softcover - 9783330065765
35,90 €
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Beschreibung

Purine can be considered as the most ubiquitous and functional N-heterocyclic compounds in nature. Structural modifications of natural purines, particularly using isosteric ring systems, have been in the focus of many drug discovery programs. Due to the structural similarity between the pyrazolo[1,5-a][1,3,5]triazine scaffold and the purine system, modifications of this scaffold have given rise to a lot of bioactive agents which could interact with targets of biogenic purines. The present review to the best of our knowledge about synthesis of pyrazolo[1,5-a][1,3,5]triazine scaffold as enzyme inhibitors with therapeutic value.

Details

Verlag LAP LAMBERT Academic Publishing
Ersterscheinung 30. März 2017
Maße 22 cm x 15 cm x 0.4 cm
Gewicht 96 Gramm
Format Softcover
ISBN-13 9783330065765
Seiten 52

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