Autorenfreundlich Bücher kaufen?!
Beschreibung
This work covers sequence-based protein homology detection, a fundamental and challenging bioinformatics problem with a variety of real-world applications. The text first surveys a few popular homology detection methods, such as Position-Specific Scoring Matrix (PSSM) and Hidden Markov Model (HMM) based methods, and then describes a novel Markov Random Fields (MRF) based method developed by the authors. MRF-based methods are much more sensitive than HMM- and PSSM-based methods for remote homolog detection and fold recognition, as MRFs can model long-range residue-residue interaction. The text also describes the installation, usage and result interpretation of programs implementing the MRF-based method.
Using MRFalign
Details
| Verlag | Springer International Publishing |
| Ersterscheinung | 03. März 2015 |
| Maße | 23.5 cm x 15.5 cm |
| Gewicht | 119 Gramm |
| Format | Softcover |
| ISBN-13 | 9783319149134 |
| Seiten | 51 |
Schlagwörter
Herstellerinformationen
Bekannt durch
