Protein engineering of CEA and its receptors

single measurment of the two -biochemical tumor markers were carried out in serum samples obtained from healthy donors , breast benign patients ,and breast cancer patients .Mean values of these tumor markers in breast cancer patients were significantly higher than that found in healthy normal or patients with benighn breast tumors .The cytosolic CEA concentration was determined in the tumor, benighn and normal tissue of breast cancer patients . significant differences between values from tumor and normal specimens were found . There was no correlation between the preoperative levels of serum CEA in the patients with carcinoma. Also, CEA in cytosol did not correlate with either stage or histology .