Prevalence of ESBL-E isolated from blood cultures in Africa

Extended-spectrum beta-lactamase producing Enterobacteriaceae (ESBL-E) have been isolated from many regions of the world. Epidemiological studies are being conducted in Europe, North America, and Asia. No study has however been conducted in Africa to determine the prevalence and distribution of ESBLs on the continent. This literature review aimed at describing the prevalence of ESBL-E isolated from blood cultures, as well as the ESBL genes involved at the international level. Our focus was mainly on Africa. The prevalence of ESBL-E differs from one country to another. The results of our literature review however indicate that class A ESBLs prevail over the other types. We took into consideration articles focusing on various types of samples to assess the prevalence of ESBL-E, but information on isolates from blood cultures is limited. The worldwide prevalence of ESBL-E has increased over time. Evidence of ESBL-E can be found in all regions of the world. Studies conducted in Africa mainly focused on the Northern and Eastern parts of the continent, while only rare studies were carried out in the rest of the continent.