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Beschreibung
PEGylation technology and key applications are introduced by this topical volume. Basic physical and chemical properties of PEG as basis for altering/improving in vivo behaviour of PEG-conjugates such as increased stability, improved PK/PD, and decreased immunogenicity, are discussed. Furthermore, chemical and enzymatic strategies for the coupling and the conjugate characterization are reported. Following chapters describe approved and marketed PEG-proteins and PEG-oligonucleotides as well as conjugates in various stages of clinical development.
Details
| Verlag | Springer Basel |
| Ersterscheinung | 18. September 2009 |
| Maße | 24.4 cm x 17 cm |
| Gewicht | 623 Gramm |
| Format | Hardcover |
| ISBN-13 | 9783764386788 |
| Seiten | 290 |
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