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Beschreibung
This book focuses on the three most important aspects of ageing research: nutrition, physical exercise and epigenetics. The contributors discuss ways that age-related epigenetic imprints such as DNA methylation and histone acetylation are modified by these two interventions. The emphasis on epigenetics helps to illuminate the underlying mechanisms of anti-ageing interventions, as ageing and disease are predominately epigenetic phenomena.
Among the highlights are chapter-length discussion of such topics as: how anti-inflammatory action of calorie restriction underlies the retardation of ageing and age-related diseases (Chapter 3); epigenetic modification of gene expression by exercise (Chapter 5); the role of functional foods and their bioactive components in bone health (Chapter 8); and an account of the first decade of a study of calorie restriction in nonhuman primates, conducted by the National Institute on Ageing.
Details
| Verlag | Springer International Publishing |
| Ersterscheinung | 06. Oktober 2016 |
| Maße | 23.5 cm x 15.5 cm |
| Gewicht | 493 Gramm |
| Format | Softcover |
| ISBN-13 | 9783319357263 |
| Seiten | 278 |
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