Nutrigenomics : Food Genome Interactions

Periodontal disease is an inflammatory process involving progressive, episodic loss of the periodontal attachment apparatus including gingiva, cementum, periodontal ligament, and alveolar bone, resulting ultimately in tooth loss in susceptible patients.There is an abundance of both empirical evidence and substantial theoretical justification for accepting the widespread belief that periodontal diseases have more than one cause i.e.they are of multifactorial etiology and complex in nature. Susceptibility to periodontal diseases involves the interplay between genetic, bacterial, environmental and nutritional factors. Common dietary chemicals act on the human genome,either directly or indirectly, to alter gene expression or structure. Genes are important in determining the function,but nutrition is able to modify the degree of gene expression.Some individuals who are overtly healthy as they reach young adulthood will begin to experience the complications of chronic diseases such as cardiovascular disease, arthritis and Alzheimer¿s disease, whereas others will reach their 80s with minimal evidence of these debilitating conditions. So, Nutrition-Gene Interactions justified to an extent