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Novel molecular targets for genistein in prostate cancer cells

Novel molecular targets for genistein in prostate cancer cells

von James Kumi-Diaka und Kendra Merchant
Softcover - 9783838338842
49,00 €
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Beschreibung

Genistein is a major isoflavone constituent of soy that has been shown to inhibit growth proliferation and induce apoptosis in cancer cells. The mechanism of genistein-induced cell death and potential molecular targets for genistein in LNCaP prostate cancer cells was investigated using several techniques. The chemosensitivity of genistein towards prostate cancer cells was investigated using the ATP and MTS assays and apoptosis induction was determined using apoptosis and caspase assays. Several molecular targets were also identified using cDNA microarray and RT-PCR analysis.

Details

Verlag LAP LAMBERT Academic Publishing
Ersterscheinung 15. Januar 2010
Maße 22 cm x 15 cm x 0.7 cm
Gewicht 167 Gramm
Format Softcover
ISBN-13 9783838338842
Seiten 100