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Novel Antimalarial Drugs

Novel Antimalarial Drugs

von Bhupendra Singh und Dipak Chetia
Softcover - 9783659253713
49,00 €
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Beschreibung

Development of resistance has severely limited the choice of available antimalarial drugs, which clearly highlights the urgent need of novel chemotherapeutic agents for the treatment of malaria. The purpose of this study was to develop new potential antimalarial agents with Amino-quinoline ring. A series of novel Amino-quinoline Mannich base drug molecules have been synthesized.The synthesized molecules were evaluated for in vitro and in vivo antimalarial activity against the chloroquine sensitive 3D7 (West Africa) and RKL-2 strain of Plasmodium falciparum and rodent malaria parasite Plasmodium yoelii (strain N-67) in Swiss mice model.

Study of Amino-quinoline Mannich Bases

Details

Verlag LAP LAMBERT Academic Publishing
Ersterscheinung 13. Oktober 2012
Maße 22 cm x 15 cm x 0.6 cm
Gewicht 137 Gramm
Format Softcover
ISBN-13 9783659253713
Seiten 80

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