Neurophysiological Abnormalities In Optic Neuritis

Introduction:Optic neuritis (ON) represents the first demyelinating event in multiple sclerosis (MS) in more than 20% of cases. The initial data of visual evoked potentials vary from one patient to another.The aim of this work is to study the abnormalities of optic neuritis in relapsing-remitting MS and to analyze these abnormalities in relation to disability, number of relapses and imaging.Methods:We performed a longitudinal descriptive and retrospective study on MS patients followed at the neurology department of Charles Nicolle Hospital until 2018. We included patients classified as relapsing-remitting MS according to the 2010 McDonald criteria and with a minimum follow-up time of 5 years. The average disease duration was 10 years. The mean duration of EPI from the time of diagnosis was 10 months.This study shows the importance of EPI data in predicting the course of relapsing-remitting MS. The axonal or axon-demyelinating forms that may exist at early stages of the disease are associated with a rapid progression of disability.