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Hardcover - 9781588294852
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Beschreibung
A panel of internationally recognized research scientists and clinical investigators brings together a diverse collection of readily reproducible methods for identifying and quantifying a large number of specific genetic abnormalities associated with the broad spectrum of myeloid malignancies. Highlights include techniques for the detection of BCR-ABL mutations and resistance to imatinib mesylate, detection of the FIP1L1-PDGFRA fusion in idiopathic hypereosinophilic syndrome and chronic eosinophilic leukemia, classification of AML by DNA-oligonucleotide microarrays, and detection of the V617F JAK2 mutation in myeloproliferative disorders. In addition to gene rearrangments, other prognostically relevant molecular lesions such as FLT3 mutations and WT-1 overexpression are covered.
Methods and Protocols
Methods and Protocols
Details
| Verlag | Humana Press |
| Ersterscheinung | 21. November 2020 |
| Maße | 23.5 cm x 15.5 cm |
| Gewicht | 487 Gramm |
| Format | Softcover |
| ISBN-13 | 9781607614562 |
| Auflage | 1st edition 2006 |
| Seiten | 307 |
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