Morphometric evaluation of Endometrial Lesions: A Comprehensive Review

The endometrium is subject to rapid cycling with proliferation, differentiation, and breakdown under hormonal influences, and therefore it represents a good model for the study of the interplay of cell proliferation and death. The mechanism of carcinogenesis in the endometrium is strongly associated in most cases with unopposed estrogen influence on the mucosal turnover. Image analysis (IA) includes automated or semi-automated computer- based methods in which image information is digitized, captured, stored and subjected to quantitation of image features. This process might also be referred to as¿quantitative digital imaging¿. Other terms commonly employed include ¿image cytometry¿, ¿cytophotometry¿, ¿static cytometry¿ and ¿micro-spectro-photometry¿.