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Beschreibung
Human platelet HPA-1 polymorphism is embedded in the N-terminal plexin/semaphorin/integrin (PSI) domain of the ¿3 chain of the platelet integrin ¿IIb¿3. HPA-1 polymorphism is responsible for neonatal alloimmune thrombocytopenia (NAITP). T-helper response drives anti-HPA-1a production and the putative dominant T-helper epitope is likely to be an important contributory factor in the immunogenicity of HPA-1a. This book provides detailed insight into the molecular mechanism behind of anti-HPA-1a platelet alloimmunization.
Details
| Verlag | LAP LAMBERT Academic Publishing |
| Ersterscheinung | 12. Dezember 2013 |
| Maße | 22 cm x 15 cm x 1.8 cm |
| Gewicht | 447 Gramm |
| Format | Softcover |
| ISBN-13 | 9783659444111 |
| Seiten | 288 |
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