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Mitochondrial Dynamics and Neurodegeneration

Softcover - 9789400799479
160,49 €
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Hardcover - 9789400712904
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Beschreibung

Mitochondria are essential organelles in eukaryotic cells that control such diverse processes as energy metabolism, calcium buffering, and cell death. Recent studies have revealed that changes in mitochondrial morphology by fission and fusion, a process known as mitochondrial dynamics, is particularly important for neuronal function and survival. Defects in this process are commonly found in neurodegenerative diseases, offering a new paradigm for investigating mechanisms of neurodegeneration. To provide researchers working on neurodegenerative diseases and mitochondria with updated information on this rapidly progressing field, we have invited experts in the field to critically review recent progresses and identify future research directions. The topics include genetics of mitochondrial dynamics, mitochondrial dynamics and bioenergetics, autophagy, apoptosis, and axonal transport, and its role in neurological diseases, including Alzheimer’s, Parkinson’s, and Huntington’s diseases.

Details

Verlag Springer Netherland
Ersterscheinung 18. Oktober 2014
Maße 23.5 cm x 15.5 cm
Gewicht 417 Gramm
Format Softcover
ISBN-13 9789400799479
Seiten 260

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