Metabolic Oncology

Human metabolism and climate change can modulate oncogenic transformation. The global warming produces increased acidity and atmospheric carbon dioxide resulting in extremophilic archaeal symbiosis in humans. The archaeal symbiosis results in neanderthalisation of humans. The archaea induced uncoupling proteins producing the primitive Warburg phenotype and stem cell metabolonomics. The archaeal metabolites of cholesterol digoxin, bile acids and short chain fatty acids induce uncoupling proteins. There is stem cell conversion are markedly increased along with genesis of the archaeal phenotype in cancer. In cancer there is somatic cell transformation to stem cell and lose of function. This leads to evolution of the cancer phenotype.