Mechanisms of Oncogenesis

Pediatric Cancer Mechanisms of Cancer Growth and Progression . 129 EnidGilbert-BarnessandPawiniKhanna 9 Carcinogenetic Pathway of Malignant Melanoma . . . . . . . . . . 149 KennethB. CalderandMichaelB. Morgan 10 Ewing Sarcoma: Molecular Characterization and Potential Molecular Therapeutic Targets . . . . . . . . . . . . . . . . . . . . 159 MarilynM. BuiandPaulJ. Zhang 11 Molecular Mechanisms of Central Nervous System Metastasis. . . 167 NicoleD. Riddle,MumtazVRojiani,StevenBrem, andAmynM. Rojiani 12 Carcinogenesis of Human Papillomavirus in Head and Neck Squamous Cell Carcinoma. . . . . . . . . . . . . . . . . . . . 179 DahuiQin vii viii Contents 13 Postmenopausal Hormone Replacement Therapy and Breast Cancer ¿ Clinicopathologic Associations and Molecular Mechanisms . . . . . . . . . . . . . . . . . . . . . . 187 GezaAcsandMichaelJ. Wagoner 14 Carcinogenesis of Lung Cancer . . . . . . . . . . . . . . . . . . . . 203 JeffreyAufmanandFarahKhalil 15 Genesis of Barrett¿s Neoplasia: Current Concepts. . . . . . . . . . 213 DomenicoCoppola,NellyA. Nasir,andLeslieTurner 16 Genesis of Pancreatic Ductal Neoplasia. . . . . . . . . . . . . . . . 225 BarbaraA. CentenoandGregoryM. Springett 17 Recent Advances in the Pathogenesis of Pancreatic Endocrine Neoplasms. . . . . . . . . . . . . . . . . . . . . . . . . . 237 OmieMills,NellyA. Nasir,JonathanR. Strosberg, LarryK.