Management of abdominal thrombosis in non-cirrhotic patients:

The objective of this work was to describe the profile of non-cirrhotic patients with abdominal thrombosis for whom the search for thrombophilia was indicated and to determine its impact on treatment. This was a retrospective study including 48 patients followed for abdominal thrombosis over a 12-year period. The mean age was 47 years. Portal location was the most frequent (92%). An etiology was identified in 28 patients: mainly local causes (n=14). Congenital thrombophilia was investigated in 33 patients. It was indicated particularly in young subjects (less than 50 years old). A probable constitutional deficiency in coagulation inhibitors was retained in 3 patients. Acquired thrombophilia was related to antiphospholipid antibody syndrome (n=1) and/or hyperhomocysteinemia (n=6). Anticoagulation was indicated in 35 patients. In multivariate analysis, only the totality of the thrombosis was a determining factor in the decision to start treatment. In contrast, no factor was significantly associated with the decision to prolong anticoagulation.