Ki67 in breast carcinoma

Ki67 in breast carcinoma: correlation with major prognostic factorsBreast cancer (BC) is a major public health problem in Tunisia and worldwide. Few studies have focused on the correlation of Ki67 index with conventional prognostic factors of BC. The objectives of this work were to study through a series of cases, the clinico-pathological characteristics of CS and to evaluate the correlation of the Ki67 index with the main prognostic factors.A retrospective descriptive study of CS cases over a five-year period was performed.A total of 69 cases were collected. The ki67 index was ¿ 20% in 58% of the cases. We found a statistically significant correlation between Ki67 and SBR grade (p=0.02), architectural grade (p=0.05), mitotic grade (p=0.04), estrogen receptor status (p=0.03), progesterone receptor status (p=0.03) and molecular classification (p<10-3).Our study had established that the Ki67 index correlated with many conventional histopronostic factors of CS. This is a further argument for the prognostic role of Ki67 index in SC.