Investigation into the Antioxidant Potentials of Tannic & Gallic Acids

Various prospective studies have indicated the antioxidant potency of tannic and gallic acids in several models. However, there is no clear-cut evidence revealing that their reported antioxidant properties remain potent regardless of the lipid sources and proxidants employed for the oxidative assault. Hence, this study sought to investigate the antioxidant properties of tannic and gallic acids in several tissues lipids peroxidation by several pro-oxidants (FeSO4, SNP, Cyclophosphamide and Acetaminophen) in vitro. However, my results indicated that Fe (II) showed the highest proxidative effects in both the liver and brain lipids. Furthermore, tannic and gallic acids demonstrated potent inhibitory effects against lipid peroxidation in both cerebral and hepatic lipids regardless of the pro-oxidant employed, indicating that tannic and gallic acids employ diverse mechanisms to protect critical macromolecules from free radical attack. To this end, there is a dire need to exploit the protective benefits of tannic and gallic acids as potential exogenous antioxidants specifically; against lipid peroxidation with a view to providing solution to the global oxidative stress menace.