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Insilico docking studies of red pigment isolated from marine vibrio sp

Insilico docking studies of red pigment isolated from marine vibrio sp

von Shivakrishna Pabba
Softcover - 9783639661422
59,90 €
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Beschreibung

Prodigiosin was isolated from fermented broth of isolated marine bacterial strain Vibrio sp. The compound was characterized, and evaluated for its antimicrobial properties. The isolated strain was molecularly identified based on 16S rRNA based phylogenetic analysis. This molecular analysis data suggested that this strain is closely related to Vibrio sp. The extract was purified and characterized by spectral data using NMR and MASS and confirmed as analogue 2,2'-[3-methoxy-1'amyl-5'-methyl-4-(1''-pyrryl)] Prodigiosin structure. Prodigiosin exhibited antioxidant and broad spectrum antimicrobial properties against gram negative and gram positive strains. Molecular docking study with different cancer targets revealed that this compound it may be a potential candidate at pharmaceutical sector.

Prodigiosin and Cycloprodigiosin

Details

Verlag Scholars' Press
Ersterscheinung 18. Juli 2014
Maße 22 cm x 15 cm x 0.7 cm
Gewicht 173 Gramm
Format Softcover
ISBN-13 9783639661422
Seiten 104

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