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Beschreibung
Bacterial CpG-DNA sequences not only serve for genetic information but act as "danger" signal to alert immune cells such as macrophages and dendritic cells. CpG-DNA directly causes activation of these members of the innate immune system yielding in up-regulation of co-stimulatory molecules and pro-inflammatory cytokines. As such they act as "natural" adjuvants to promote protective Th1 polarized T cell immune responses. This book is the first comprehensive review of the data emerging in this field.
Details
| Verlag | Springer Berlin |
| Ersterscheinung | 26. September 2011 |
| Maße | 23.5 cm x 15.5 cm |
| Gewicht | 406 Gramm |
| Format | Softcover |
| ISBN-13 | 9783642640773 |
| Seiten | 246 |
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