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Histone Deacetylases

Hardcover - 9781588294999
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Softcover - 9781617376023
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Softcover - 9781617376023
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Beschreibung

A panel of leading investigators summarizes and synthesizes the new discoveries in the rapidly evolving field of histone acetylation as a key regulatory mechanism for gene expression. The authors describe what has been learned about these proteins, including the identification of the enzymes, the elucidation of the enzymatic mechanisms of action, and the identification of their substrates and their partners. They also review the structures that have been solved for a number of enzymes-both alone and in complex with small molecule inhibitors-and the biological roles of the several histone deacetylases (HDAC) genes that have been knocked out in mice.

Transcriptional Regulation and Other Cellular Functions

Transcriptional Regulation and Other Cellular Functions

Details

Verlag Humana Press
Ersterscheinung 05. Januar 2006
Maße 23.5 cm x 15.5 cm
Gewicht 771 Gramm
Format Hardcover
ISBN-13 9781588294999
Seiten 352

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