Gastro-Retentive Drug Delivery System

Gastro-retentive drug delivery system (GRDDS) has gained vast popularity in the field of oral drug delivery system in recent times. It is a widely in use to retain the dosage form in the stomach for an extended period of time and release the drug slowly that can deal with many challenges associated with conventional oral delivery, including poor bioavailability. Different innovative approaches like magnetic field assisted gastro-retention, plug type swelling system, floating drug dosage systems (FDDS), swelling or expanding systems, bio/mucoadhesive systems, raft forming system, magnetic systems, modified-shape systems, super porous hydrogel system, high density system are being applied to fabricate GRDDS. This results in targeting of drug release at a specific site for the systemic and local effects.