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Beschreibung
This book discusses a broad range of basic and advanced topics in the field of protein structure, function, folding, flexibility, and dynamics. Starting with a basic introduction to protein purification, estimation, storage, and its effect on the protein structure, function, and dynamics, it also discusses various experimental and computational structure determination approaches; the importance of molecular interactions and water in protein stability, folding and dynamics; kinetic and thermodynamic parameters associated with protein-ligand binding; single molecule techniques and their applications in studying protein folding and aggregation; protein quality control; the role of amino acid sequence in protein aggregation; muscarinic acetylcholine receptors, antimuscarinic drugs, and their clinical significances.
Further, the book explains the current understanding on the therapeutic importance of the enzyme dopamine beta hydroxylase; structural dynamics and motions in molecularmotors; role of cathepsins in controlling degradation of extracellular matrix during disease states; and the important structure-function relationship of iron-binding proteins, ferritins . Overall, the book is an important guide and a comprehensive resource for understanding protein structure, function, dynamics, and interaction.Details
| Verlag | Springer Singapore |
| Ersterscheinung | 03. Juli 2020 |
| Maße | 23.5 cm x 15.5 cm |
| Gewicht | 863 Gramm |
| Format | Hardcover |
| ISBN-13 | 9789811555299 |
| Seiten | 452 |
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