Energy Landscapes of Protein Folding: From Structure to Function: Structure and Function of Intermediate States of Ankyrin Repeat Proteins

Energy Landscapes of Protein Folding: From Structure to Function: Structure and Function of Intermediate States of Ankyrin Repeat Proteins

von Christian Löw
Taschenbuch - 9783838111087
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Beschreibung

Proteins are the vital molecules in living cells and important targets for pharmaceutical and biotechnological applications. To function, they need a defined three dimensional structure. All the information necessary for a protein to achieve this conformation is encoded in its amino acid sequence. To understand the process by which a polypeptide chain folds into its three-dimensional structure (the so-called "protein folding reaction") is an essential element in structural biology. This work mainly focusses on the structural and functional characterization of partially folded intermediate states, which can accumulate during the folding process. Ankyrin Repeat proteins were choosen as model proteins, since their architectural simplicity allows the dissection of energetics to different structural elements.

Details

Verlag Südwestdeutscher Verlag für Hochschulschriften AG Co. KG
Ersterscheinung September 2015
Maße 220 mm x 150 mm x 12 mm
Gewicht 308 Gramm
Format Taschenbuch
ISBN-13 9783838111087
Auflage Nicht bekannt
Seiten 196

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