Electrochemistry of Triazolopyrimidines

Electrochemical studies on some triazolopyrimidine derivatives. Triazolopyrimidines and its derivatives are known to have many biological, pharmaceutical and analytical applications. Several triazolopyrimidine compounds have potential uses as a potent antibacterial drugs due to their higher antibacterial activity than some commercial antibiotics against bacillus subtilis, staphylococcus aureus and salmonella typhi at MIC (minimum inhibitory concentration) i.e. 10 mg/ml. Triazolopyrimidine compounds have an important potential role in cardiovascular therapeutics specially in platelet aggregation as an antiplatelet agent or anticoagulant and in many other cardiac diseases like angina, peripheral cardial diseases and stroke Because of this it was found worthwhile to investigate the redox characteristics of substituted triazolopyrimidines (1a-f) and (2a-e). This work has been carried out to investigate the electrochemical behavior of triazolopyrimidine derivatives (Ia-f), (2a-e), using cyclic voltammetry in different non-aqueous media