Effects of Gnidia stenophylla Gilg Root Extract in Swiss Albino Mice

In Ethiopia, people locally use the roots of Gnidia stenophylla Gilg (GSG) (Thymelaeaceae) to cure an array of diseases including malaria and malaria-related symptoms with no literature evidence substantiating its safety. This book, therefore, provides new literature evidence regarding the safety of using GSG aqueous root extract as a traditional remedy. The book also addresses the effect of the plant extract on body weight, food intake, hematological and biochemical parameters as well as on gross and histopathological changes of gastrointestinal tract (GIT), spleen, liver and kidney tissues after acute and chronic oral administration in Swiss albino mice. The aqueous extract mimics the traditional decoction dosage form of GSG as an antimalarial herbal remedy.