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Effects of a BMP Antagonist on Fracture Healing in a Mouse Model

Effects of a BMP Antagonist on Fracture Healing in a Mouse Model

von Alexander Mounts
Softcover - 9783330085909
35,90 €
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Beschreibung

Fracture healing is a complex process that is responsible for forming a fracture callus to stabilize the site of injury while producing new bone. Delayed fracture healing or the development of non-union as a result of failed fracture healing is a major clinical concern effecting ~10% of all treated fractures. Recent studies have shown that RAP-661, an antagonist of Bone Morphogenetic Proteins (BMP) 2 and BMP-4 binding to its receptor BMPR-1A has shown anabolic efficacy in treating bone loss associated with osteoporosis. The purpose of this study was to assess the effectiveness of the RAP-661 protein as a therapeutic agent to improve fracture healing.

Details

Verlag LAP LAMBERT Academic Publishing
Ersterscheinung 29. Mai 2017
Maße 22 cm x 15 cm x 0.4 cm
Gewicht 96 Gramm
Format Softcover
ISBN-13 9783330085909
Seiten 52