Dry Syrups for Paediatrics

Suspensions may be defined as preparations containing finely divided drug particles (the suspensoid) distributed somewhat uniformly throughout a vehicle with or without stabilizers and other additives in which drug exhibits a minimum degree of solubility hence conventional oral suspension can be administered immediately (ready to use form) and not requiring reconstitution at the time of dispensing are simply designated as ¿Oral Suspension¿. There is an important category of suspension that are available as dry powders intended for suspension in liquid vehicles. These are dry mixtures containing the drug and suitable suspending and dispersing agents to be diluted and agitated with a specific quantity of vehicle, most often purified water. Drugs that are instable if maintained for extended periods in the presence of aqueous vehicle (eg., many antibiotic drugs) are frequently supplied as dry powder mixtures for reconstitution at the time of dispensing. This type of preparation is designated in the USP by a title ¿for Oral Suspension¿. The reconstituted system is the formulation of choice when the drug stability is a major concern.