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Drug-excipient-shell interactions using thermoplastic capsules

Drug-excipient-shell interactions using thermoplastic capsules

von Georgios Imanidis, Martin Kuentz und Zdravka Misic
Softcover - 9786202007146
71,90 €
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Beschreibung

This book introduced novel starch-based thermoplastic capsules (S-PVA-Cs) and demonstrated their advantage over SGCs with respect to hydrophilic lipid-based formulations. Release studies in biorelevant media revealed differences in how formulations hydrated and interacted with the shell material. Drug-excipient-shell interactions were observed in various capsule types (SGCs, S-PVA-Cs, and VegaGels®) at different levels of biopharmaceutical in vitro testing. A better mechanistic understanding was attained that may guide future development of soft capsule products.

Details

Verlag LAP LAMBERT Academic Publishing
Ersterscheinung 23. September 2019
Maße 22 cm x 15 cm x 1.3 cm
Gewicht 304 Gramm
Format Softcover
ISBN-13 9786202007146
Seiten 192

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