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Beschreibung
This book introduced novel starch-based thermoplastic capsules (S-PVA-Cs) and demonstrated their advantage over SGCs with respect to hydrophilic lipid-based formulations. Release studies in biorelevant media revealed differences in how formulations hydrated and interacted with the shell material. Drug-excipient-shell interactions were observed in various capsule types (SGCs, S-PVA-Cs, and VegaGels®) at different levels of biopharmaceutical in vitro testing. A better mechanistic understanding was attained that may guide future development of soft capsule products.
Details
| Verlag | LAP LAMBERT Academic Publishing |
| Ersterscheinung | 23. September 2019 |
| Maße | 22 cm x 15 cm x 1.3 cm |
| Gewicht | 304 Gramm |
| Format | Softcover |
| ISBN-13 | 9786202007146 |
| Seiten | 192 |