Drug Designing and Heterocyclic Chemistry

Heterocyclic systems are important ingredient of large number of naturally occurring and synthetic drugs. Synthetic potential and biological activity of heterocycles selected for present studies have been explored to maximum extent. Versatile utility of these ring systems in various aspects of medicinal chemistry evoked widespread research and attention. Alpha substituted hydroxyl amine in particular alkoxyphthalimides aminoxy and related derivatives are a class of compounds with the object of considerable interest due to their application in different field including pharmaceuticals. Combination of these two moieties in a molecule may cause appreciable modification in their biological behaviors and other life activities. This engendered the idea to synthesize a number of biologically active heterocycles containing this functionally. Present investigation forms a part of comprehensive task to develop new pathways, to obtain newer molecules and to screen their antimicrobial activity.