Development of sensitive and specific diagnostic assay

Sheeppox (SP) is an infectious disease of small ruminants responsible for high economic losses to developing country such as India. The genus Capripox virus comprises three members namely, sheeppox virus (SPV), goatpox virus (GPV) and lumpy skin disease virus (LSDV) affecting sheep, goats and cattle, respectively. Sheeppox disease is associated with significant production losses because of reduced milk yield, decreased weight gain, increased abortion rates in pregnant animals, damage to wool and hides, increased susceptibility to pneumonia and other secondary infections. Sheeppox (SP) is responsible for high economic losses to developing country such as India. Keeping these problems in mind, the presented work on development and evaluation of loop mediated isothermal amplification (LAMP) assay for detection of SPVwas taken up.