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Beschreibung
A number of autoimmune disease models have been used to examine the anti-inflammatory and immunosuppressive effects of tolerogenic dendritic cells (tDCs). The aim of the present study was to investigate whether rosiglitazone-mediated DC (Rosi-DC) therapy suppressed arthritis in a collagen-induced arthritis (CIA) mouse model. The results presented herein show that type II collagen-pulsed Rosi-DCs ameliorate the inflammation associated with CIA via the induction of Treg cell population. These results suggest that rosiglitazone-mediated DCs hold promise as a novel therapeutic strategy for RA.
-Rheumatoid arthritis-
Details
| Verlag | LAP LAMBERT Academic Publishing |
| Ersterscheinung | 20. September 2016 |
| Maße | 22 cm x 15 cm x 0.4 cm |
| Gewicht | 96 Gramm |
| Format | Softcover |
| ISBN-13 | 9783659954856 |
| Seiten | 52 |
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