CORONARY SPASM

Coronary heart disease is one of the most common cardiovascular diseases affecting the world's population. It is the leading cause of death in both developed and developing countries. Its basic pathophysiological mechanism is straightforward: a mismatch between myocardial oxygen supply and demand leads to more or less extensive ischemia, manifesting itself as stable or unstable angina, myocardial infarction or sudden cardiac death. Once considered an exclusively atherosclerotic disease, where cardiovascular risk factors such as : tobacco, diabetes, dyslipidemia... an accumulation of cholesterol in the coronary arterial wall (atherosclerotic plaque) reduces the internal lumen, causing imbalance and symptoms. In addition, thromboembolic phenomena associated with plaque rupture exacerbate the imbalance, precipitating acute coronary syndromes (ACS).