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Softcover - 9783642436529
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Beschreibung
This thesis presents a novel coarse-grained model of DNA, in which bases are represented as rigid nucleotides. The model is shown to quantitatively reproduce many phenomena, including elastic properties of the double-stranded state, hairpin formation in single strands and hybridization of pairs of strands to form duplexes, the first time such a wide range of properties has been captured by a coarse-grained model. The scope and potential of the model is demonstrated by simulating DNA tweezers, an iconic nanodevice, and a two-footed DNA walker — the first time that coarse-grained modelling has been applied to dynamic DNA nanotechnology.
Details
| Verlag | Springer Berlin |
| Ersterscheinung | 07. Juli 2012 |
| Maße | 23.5 cm x 15.5 cm |
| Gewicht | 453 Gramm |
| Format | Hardcover |
| ISBN-13 | 9783642305160 |
| Auflage | 2012 |
| Seiten | 176 |
Schlagwörter
Biophysics, Biophysik, Complex Systems, Kybernetik und Systemtheorie, Mathematische Physik, Nanotechnologie, Nanotechnology, Physik der kondensierten Materie (Flüssigkeits- und Festkörperphysik), Polymers, Soft and Granular Matter, Technische Anwendung von Polymeren und Verbundwerkstoffen, Theoretical - Mathematical and Computational Physics
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