Cloning and Expression of the Full and Truncated MOMP of C.trachomatis

Administration of Prophylactic vaccine for STDs still is a cutting-edge of prevention, control and elimination of such infections. Among the common causes of STDs, chlamydia trachomatis is a silent, turbulent and unfortunately neglected disease which damages human genital tract function. This Gram-negative obligate intracellular bacterium with unique life cycle and immunopathogenesis result in serious complications, such as Endometritis, pelvic inflammatory disease (PID), ability to ease HIV transmission, cofactor in human papilloma virus (HPV)-induced cervical neoplasia, and infertility. Because of the all above, vaccination is considered to be the most cheaper and reliable way to escape from unrestrained exacerbation states of infection than any other prevalence program. Among a number of potential vaccine candidate, the major outer membrane protein (MOMP) is a vanguard of subunit vaccine candidates.